Duck Amuck is a surreal 1951 animated cartoon directed by Chuck Jones and produced by Warner Bros. Cartoons. The short was released in early 1953 by The Vitaphone Corporation, the short subject division of Warner Bros. Pictures, as part of the Merrie Melodies series. It stars Daffy Duck, who is tormented by a sadistic, unseen animator who constantly changes Daffy's location, clothing, voice, physical appearance, and even shape. Pandemonium reigns throughout the cartoon as Daffy attempts to steer the action back to some kind of normality, only for the animator to either ignore him or, more frequently, to over-literally interpret his increasingly frantic demands.

In 1994 it was voted #2 of The 50 Greatest Cartoons of all time by members of the animation field, and was included on Looney Tunes Golden Collection: Volume 1.

According to director Chuck Jones, this film demonstrated for the first time that animation can create characters with a recognizable personality, independent of their appearance, milieu, or voice. Although in the end, the animator is revealed to be Daffy's friend and rival Bugs Bunny (who famously declares "Ain't I a stinker?"), according to Jones the ending is just for comedic value: Jones (the director) is speaking to the audience directly, asking "Who is Daffy Duck anyway? Would you recognize him if I did this to him? What if he didn't live in the woods? Didn't live anywhere? What if he had no voice? No face? What if he wasn't even a duck anymore?" In all cases, it is obvious that Daffy is still Daffy; not all cartoon characters can claim such distinctive personality.

Duck Amuck is included in the compilation film, The Bugs Bunny-Road Runner Movie, along with other favorite Chuck Jones cartoons including What's Opera, Doc?

Mel Blanc does the voices. It was directed by Chuck Jones with a story by Michael Maltese. The film contains many examples of self-referential humor, breaking the fourth wall.

In 1999 the film was deemed "culturally significant" by the United States Library of Congress and selected for preservation in the National Film Registry. This was the second of three animated shorts by Jones to receive this honor (the others are 1957's What's Opera, Doc? and 1955's One Froggy Evening). Jones has the distinction of being the only director (as of 2006) with three animated shorts in the registry.

The cartoon's plot was essentially replicated in one of Jones' later cartoons, Rabbit Rampage (1955), in which Bugs Bunny turns out to be the victim of the silly animator (Elmer Fudd). A similar plot was also included in an episode of Baby Looney Tunes, only Bugs was the victim, Daffy was the animator, and it was made on a computer instead of a pencil and paper.

In Looney Tunes Comics Issue #94, Bugs Bunny gets his back at Daffy Duck by making him the victim, in switching various movie roles, from Duck Twacy in "Who Killed Daffy Duck," a video game character, and a talk show host, and they always wound up with Daffy starring in Moby Dick (the story's running gag). After this, Bugs comments, "Eh, dis guy needs a new agent."

Daffy is harassed by an unseen, trickster animator, who keeps changing backgrounds on him, messes with the soundtrack, switches props and humilates him with buffoonish costumes. Written by Paul Penna

Daffy Duck plays a Musketeer, but as he advances on his enemy, the background disappears; Daffy demands the proper scenery, and an animator paints a completely inappropriate background - the start of a running duel between Daffy and the unseen animator who changes backgrounds, Daffy's appearance, the soundtrack, and even the film projection under Daffy's feet, forcing the mad mallard to improvise his performance and leaving him screaming for the animator's head. Written by Michael Daly